Dexamethasone - CAS 50-02-2

Dexamethasone is a glucocorticoid receptor agonist and IL receptor modulator with anti-inflammatory, immunosuppressive, and apoptosis-inducing activities. It inhibits the production of inflammatory miRNA-155 exosomes in macrophages, significantly reduces inflammatory cytokine expression in neutrophils and monocytes, suppresses LPS-induced macrophage inflammation, and induces autophagy. It is commonly used to induce animal models of depression, muscle atrophy, and hypertension, and holds potential in COVID-19 research.

Glucocorticoid Receptor, ADC Cytotoxin, Autophagy, Mitophagy, SARS-CoV, IL Receptor, Complement System, Antibiotic, Antibacterial

Antibody-drug Conjugate/ADC Related, Immunology/Inflammation, Endocrinology/Hormones, Autophagy, Microbiology/Virology

50-02-2

0.9991

C22H29FO5

392.46

F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(CO)=O)(O)[C@H](C)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]

-20°C

Ice Packs

Small Compound