DFKBP-1 - CAS 1799711-22-0

DFKBP-1 is a potent PROTAC-based FKBP12 degrader incorporating the FKBP12 ligand SLF, the Thalidomide-based cereblon ligand, and a linker[1].

PROTACs, FKBP

PROTAC, Apoptosis, Immunology/Inflammation, Autophagy

1799711-22-0

C53H64N6O14

1009.11

O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2OCC(NCCCCNC(CCC(NC4=CC([C@H](OC(=O)[C@H]5N(C(C(C(CC)(C)C)=O)=O)CCCC5)CCC6=CC(OC)=C(OC)C=C6)=CC=C4)=O)=O)=O

-20°C

Ice Packs

PROTAC