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DGKα-IN-2 - CAS 2648556-92-5
DGKα-IN-2 - CAS 2648556-92-5
SKU:MF-0157481-01
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Product Details
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Bioactivity
DGKα-IN-2 (example 48), a potent DGKα inhibitor with an IC50 of 0.9 nM, significantly enhances the anti-tumor efficacy of anti-PD-1 therapy by amplifying T cell proliferation and function, making it a valuable agent for cancer and immunological research.
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Target
Others
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Related Pathways
Others
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CAS Number
2648459
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Molecular Formula
C23H22F3N3O4
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Molecular Weight
461.43
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SMILES
C(N)(=O)C1=C(C=2C(N(C)C1=O)=CC=CC2)N3CCC(OC4=CC=C(OC(F)(F)F)C=C4)CC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound