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DGKα-IN-8 - CAS 2886717-70-8

DGKα-IN-8 - CAS 2886717-70-8

SKU:MF-0157488-01

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  • Bioactivity

    DGKα-IN-8 (Example 51), a potent diacylglycerol kinase alpha (DGKα) inhibitor, exhibits an IC50 of 22.491 nM and an EC50 of 0.256 nM. It is applicable in cancer research, particularly for solid tumors, and in studies of viral infections such as HIV and hepatitis B virus [1].

  • Target

    Others, HIV Protease

  • Related Pathways

    Others, Proteases/Proteasome, Microbiology/Virology

  • CAS Number

    2886639

  • Molecular Formula

    C23H19ClF3N5O

  • Molecular Weight

    473.88

  • SMILES

    N(CC(F)F)(C=1C=2C(C3=C(N1)N=NN3C)=CC(Cl)=CC2)C4=CC(C#CC(C)(C)O)=CC(F)=C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound