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DGKα-IN-8 - CAS 2886717-70-8
DGKα-IN-8 - CAS 2886717-70-8
SKU:MF-0157488-01
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Product Details
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Bioactivity
DGKα-IN-8 (Example 51), a potent diacylglycerol kinase alpha (DGKα) inhibitor, exhibits an IC50 of 22.491 nM and an EC50 of 0.256 nM. It is applicable in cancer research, particularly for solid tumors, and in studies of viral infections such as HIV and hepatitis B virus [1].
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Target
Others, HIV Protease
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Related Pathways
Others, Proteases/Proteasome, Microbiology/Virology
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CAS Number
2886639
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Molecular Formula
C23H19ClF3N5O
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Molecular Weight
473.88
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SMILES
N(CC(F)F)(C=1C=2C(C3=C(N1)N=NN3C)=CC(Cl)=CC2)C4=CC(C#CC(C)(C)O)=CC(F)=C4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound