DGK-IN-9 - CAS 3081525-23-4

DGK-IN-9 (Compound 15) is an orally active and selective inhibitor of DGKζ with an IC50 of 6.1 nM. It is capable of activating IL-2 expression in Jurkat-IL2 nanoluc cells with an EC50 of 153 nM. DGK-IN-9 is applicable in tumor research.

Interleukin, Others

Others, Immunology/Inflammation

3081498

C25H22F4N6O2S

546.54

O=C(NC1=CC=C(OC=2C=CC=CC2F)C(=C1N(C)CCNC)C(F)(F)F)C3=NC(=CS3)C=4C=NN=CC4

-20°C

Ice Packs

Small Compound