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DGN462 - CAS 1394079-41-4
DGN462 - CAS 1394079-41-4
SKU:MF-0022094-01
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Product Details
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Bioactivity
DGN462 is an effective DNA alkylating agent with anti-tumor activity, as in acute myeloid leukemia (AML) . DGN462 can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .
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Target
ADC Cytotoxin, DNA Alkylator/Crosslinker
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Related Pathways
DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related
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CAS Number
1394034
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Molecular Formula
C53H59N5O9S
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Molecular Weight
942.13
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SMILES
O=C1N2C=3C(C[C@]2(CNC=4C1=CC(OC)=C(OCC5=CC(N(CCOCCOCCOC)CC(C)(C)S)=CC(COC6=C(OC)C=C7C(=C6)N=C[C@]8(N(C7=O)C=9C(C8)=CC=CC9)[H])=C5)C4)[H])=CC=CC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound