DGN549-C - CAS 2058075-34-4

DGN549-C is a novel compound featuring a cleavable ADC (antibody-drug conjugate) linker composed of valine-alanine (va) and a PBD (pyrrolobenzodiazepine) dimer. This compound possesses a unique DNA-alkylating cytotoxic payload, DGN549, which is utilized in the development of ADCs.

Drug-Linker Conjugates for ADC

Antibody-drug Conjugate/ADC Related

2058037

C60H61N9O12

1100.199

[H][C@@]12Cc3ccccc3N1C(=O)c1cc(OC)c(OCc3cc(COc4cc5N=C[C@]6([H])Cc7ccccc7N6C(=O)c5cc4OC)cc(NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)CCCCC(=O)NCCN4C(=O)C=CC4=O)c3)cc1NC2 |c:30,80|

-20°C

Ice Packs

Small Compound