DGY-08-097 - CAS 2414414-50-7

DGY-08-097 is a novel HCV NS3 degrader, reducing susceptibility to resistance mutations, potently inhibiting HCV in a cellular infection model, exhibiting the most potent degradation (DC50 of 50nM at 4h) of HCV NS3.

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2414357

C60H76N10O14

1161.3

O=C1C=2C=3C(C(=O)N1C4C(=O)NC(=O)CC4)=CC=CC3C=C(OCCOCCOCCNC(=O)C=5C=NC(C(N[C@H](C(N[C@H](C(=O)N6[C@H](C(N[C@H](C(C(NC7CC7)=O)=O)CCC)=O)[C@@]8([C@](C6)(CCC8)[H])[H])[C@@](C)(C)C)=O)C9CCCCC9)=O)=CN5)C2

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