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Molfinity

DHC-286 - CAS 2920443-08-7

DHC-286 - CAS 2920443-08-7

MF-0118602-01

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Product Details

  • Bioactivity

    DHC-286 is a molecular glue degrader that targets GSPT1. It recruits GSPT1 to the CRL4CRBN ubiquitin ligase complex, facilitating its ubiquitination and subsequent degradation via the proteasome, which induces cytotoxic effects. DHC-286 holds potential for cancer research.

  • Target

    Molecular Glues

  • Related Pathways

    PROTAC

  • CAS Number

    2920443-08-7

  • Molecular Formula

    C23H20F3N3O5

  • Molecular Weight

    475.42

  • SMILES

    O=C(NCC=1C=CC=CC1C(F)(F)F)COC2=CC=C3C(=O)N(CC3=C2)C4C(=O)NC(=O)CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC