DHFR-IN-1 - CAS 2757991-65-2

DHFR-IN-1 is a selective and potent inhibitor of DHFR (dihydrofolate reductase) (IC50: 40.71 nM) . DHFR-IN-1 exhibited some antifungal activity and good antibacterial activity against Gram-positive and Gram-negative bacteria.DHFR-IN-1 showed good synergy with Levofloxacin with FIC (partial inhibitory concentration index) = 0.249.

Antifungal, Others, Antibacterial

Others, Microbiology/Virology

2757924

C22H22N6O4S2

498.58

N(NC1=NC(=CS1)C2=CC=C(O)C=C2)=C3C=4C(NC3=O)=CC=C(S(=O)(=O)N5CCN(C)CC5)C4

-20°C

Ice Packs

Small Compound