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DHFR-IN-2 - CAS 331942-46-2
DHFR-IN-2 - CAS 331942-46-2
SKU:MF-0092673-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
DHFR-IN-2 (compound 4e) is a potent and uncompetitive inhibitor of MtDHFR, with an IC50 of 7 μM. The enzyme dihydrofolate reductase from M. tuberculosis (MtDHFR) holds high unexploited potential as a drug target due to its importance for pathogen survival. DHFR-IN-2 can be used for tuberculosis (TB) research [1].
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Target
Others, Antifolate
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Related Pathways
Others, Cell Cycle/Checkpoint
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CAS Number
331894
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Molecular Formula
C14H13NO2
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Molecular Weight
227.26
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SMILES
C(NC1=CC=CC=C1)C2=CC(C(O)=O)=CC=C2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound