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Molfinity

DHFR-IN-2 - CAS 331942-46-2

DHFR-IN-2 - CAS 331942-46-2

SKU:MF-0092673-01

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  • Bioactivity

    DHFR-IN-2 (compound 4e) is a potent and uncompetitive inhibitor of MtDHFR, with an IC50 of 7 μM. The enzyme dihydrofolate reductase from M. tuberculosis (MtDHFR) holds high unexploited potential as a drug target due to its importance for pathogen survival. DHFR-IN-2 can be used for tuberculosis (TB) research [1].

  • Target

    Others, Antifolate

  • Related Pathways

    Others, Cell Cycle/Checkpoint

  • CAS Number

    331894

  • Molecular Formula

    C14H13NO2

  • Molecular Weight

    227.26

  • SMILES

    C(NC1=CC=CC=C1)C2=CC(C(O)=O)=CC=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound