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Molfinity

DHFR-IN-5 - CAS 1142407-81-5

DHFR-IN-5 - CAS 1142407-81-5

MF-0146658-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    DHFR-IN-5, an orally active and potent inhibitor of dihydrofolate reductase (DHFR), exhibits a K_i value of 0.54 nM against the quadruple mutant Plasmodium falciparum DHFR, demonstrating anti-malarial activity.

  • Target

    DHFR, Others

  • Related Pathways

    DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others, Metabolism

  • CAS Number

    1142321

  • Molecular Formula

    C18H24N4O4

  • Molecular Weight

    360.41

  • SMILES

    O(CCCOC1=C(CCC(O)=O)C=CC=C1)C=2C(CC)=NC(N)=NC2N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound