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DHODH-IN-3 - CAS 1148126-04-8
DHODH-IN-3 - CAS 1148126-04-8
SKU:MF-0022099-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
DHODH-IN-3 is an effective inhibitor of human dihydroorotate dehydrogenase (HsDHODH) with IC50 value of 261 nM. DHODH-IN-3 binds to the ubiquinone binding cavity in DHODH with a Kiapp of 32 nM. DHODH-IN-3 has the potential to treat malaria.
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Target
Others, Dehydrogenase, DNA/RNA Synthesis
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Related Pathways
DNA Damage/DNA Repair, Others, Cell Cycle/Checkpoint, Metabolism
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CAS Number
1148126-04-8
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Molecular Formula
C17H13ClN2O2
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Molecular Weight
312.75
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SMILES
ClC=1C=C(C=CC1NC(/C(=C(/C)\O)/C#N)=O)C2=CC=CC=C2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound