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Molfinity

DHODH-IN-3 - CAS 1148126-04-8

DHODH-IN-3 - CAS 1148126-04-8

SKU:MF-0022099-01

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  • Bioactivity

    DHODH-IN-3 is an effective inhibitor of human dihydroorotate dehydrogenase (HsDHODH) with IC50 value of 261 nM. DHODH-IN-3 binds to the ubiquinone binding cavity in DHODH with a Kiapp of 32 nM. DHODH-IN-3 has the potential to treat malaria.

  • Target

    Others, Dehydrogenase, DNA/RNA Synthesis

  • Related Pathways

    DNA Damage/DNA Repair, Others, Cell Cycle/Checkpoint, Metabolism

  • CAS Number

    1148126-04-8

  • Molecular Formula

    C17H13ClN2O2

  • Molecular Weight

    312.75

  • SMILES

    ClC=1C=C(C=CC1NC(/C(=C(/C)\O)/C#N)=O)C2=CC=CC=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound