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DHODH-IN-4 - CAS 1148125-93-2
DHODH-IN-4 - CAS 1148125-93-2
SKU:MF-0019374-01
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$120.06 USD
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$120.06 USD
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Product Details
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Bioactivity
DHODH-IN-4 is a human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) inhibitor. The IC50 values of PfDHODH and HsDHODH are 4 μM and 0.18 μM, respectively. DHODH-IN-4 has antimalarial activity.
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Target
DNA/RNA Synthesis, Parasite, Dehydrogenase
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Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Metabolism, Microbiology/Virology
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CAS Number
1148030
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Purity
0.9934
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Molecular Formula
C17H12Cl2N2O2
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Molecular Weight
347.2
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SMILES
ClC1=C(C2=CC(Cl)=C(NC(/C(=C(/C)\O)/C#N)=O)C=C2)C=CC=C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound