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Molfinity

DHODH-IN-4 - CAS 1148125-93-2

DHODH-IN-4 - CAS 1148125-93-2

SKU:MF-0019374-01

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  • Bioactivity

    DHODH-IN-4 is a human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) inhibitor. The IC50 values of PfDHODH and HsDHODH are 4 μM and 0.18 μM, respectively. DHODH-IN-4 has antimalarial activity.

  • Target

    DNA/RNA Synthesis, Parasite, Dehydrogenase

  • Related Pathways

    Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Metabolism, Microbiology/Virology

  • CAS Number

    1148030

  • Purity

    0.9934

  • Molecular Formula

    C17H12Cl2N2O2

  • Molecular Weight

    347.2

  • SMILES

    ClC1=C(C2=CC(Cl)=C(NC(/C(=C(/C)\O)/C#N)=O)C=C2)C=CC=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound