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Molfinity

DHODH-IN-8 - CAS 1148126-03-7

DHODH-IN-8 - CAS 1148126-03-7

MF-0012831-01

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Product Details

  • Bioactivity

    DHODH-IN-8 has antimalarial activity. DHODH-IN-8 is an inhibitor of human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) with IC50 of 0.13 μM and 47.4 μM, and Kis of 0.016 μM and 5.6 μM, respectively.

  • Target

    Parasite, Dehydrogenase, DNA/RNA Synthesis

  • Related Pathways

    Metabolism, Microbiology/Virology, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

  • CAS Number

    1148126-03-7

  • Purity

    0.9978

  • Molecular Formula

    C17H13ClN2O2

  • Molecular Weight

    312.75

  • SMILES

    ClC1=C(C2=CC=C(NC(/C(=C(/C)\O)/C#N)=O)C=C2)C=CC=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound