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Molfinity

DI-1859 - CAS 2247061-09-0

DI-1859 - CAS 2247061-09-0

MF-0038938-01

$1,901.53 USD
$1,901.53 USD
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Product Details

  • Bioactivity

    DI-1859 is a selective, potent and covalent inhibitor of DCN1. At low nanomolar concentrations, DI-1859 inhibits the neddylation of cullin 3 in cells. DI-1859 induces a significant increase in NRF2 protein, a CRL3 substrate, in mouse liver and effectively protects mice from acetaminophen-induced liver injury.

  • Target

    Others, E1/E2/E3 Enzyme

  • Related Pathways

    Ubiquitination, Others

  • CAS Number

    2247061-09-0

  • Molecular Formula

    C30H45N5O3S

  • Molecular Weight

    555.78

  • SMILES

    CCC(=O)N[C@@H](Cc1nc2ccc(cc2s1)C(C)C)C(=O)N[C@H](CNC(=O)C(=C)CN(C)C)C1CCCCC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound