DI-404 - CAS 2187412-79-7

DI-404 is a high-Affinity Peptidomimetic the DCN1-UBC12 Protein-Protein Interaction inhibitor (Kd= 6.9 nM) . DI-404 effectively and selectively inhibits the neddylation of cullin 3 over other cullin members.

E1/E2/E3 Enzyme, Others

Others, Ubiquitination

2187326

C35H45ClN6O6S

713.29

C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H]1C=2C(OCC1)=CC=CC2)=O)CCCCN)=O)[C@H]3CCOCC3)=O)NC(CC)=O)C=4SC=5C(N4)=CC=C(Cl)C5

-20°C

Ice Packs

Small Compound