Di-Ellipticine-RIBOTAC - CAS 2767983-76-4

Di-Ellipticine-RIBOTAC is a bifunctional small molecule that effectively diminishes the r (G4C2) repeat expansion associated with c9ALS/FTD both in vitro and in vivo, showcasing therapeutic potential in amyotrophic lateral sclerosis (ALS) models.

PROTACs

PROTAC

2767983-76-4

C78H87N7O16S

1410.63

O=C(OCC)C=1C(=O)C(SC1NC=2C=CC=CC2)=CC3=CC=C(OCCOCCOCCOCCNC(=O)CCC(=O)N(CCOCCOCCOC4=CC=C5NC6=C(C5=C4)C(=C7C=NC=CC7=C6C)C)CCOCCOCCOC8=CC=C9NC%10=C(C9=C8)C(=C%11C=NC=CC%11=C%10C)C)C(O)=C3

-20°C

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PROTAC