Dicentrine - CAS 517-66-8

Dicentrine is an alkaloid-enriched fraction and the primary alkaloid of the leaves of Ocotea puberula (Lauraceae), a native Brazilian plant traditionally used by Indigenous populations for skin affections, and dicentrine further demonstrates pharmacological activity as an α1-adrenoceptor antagonist in human hyperplastic prostate tissue. Dicentrine has been evaluated using radioligand binding assays with [3H]prazosin and in vitro isometric tension experiments, confirming functional α1-adrenoceptor involvement and supporting therapeutic relevance in disorders associated with prostate hyperplasia.

Adrenergic Receptor

GPCR/G Protein, Neuroscience

443

0.9999

C20H21NO4

339.39

CN1[C@@]2(C=3C(C=4C(C2)=CC(OC)=C(OC)C4)=C5C(=CC3CC1)OCO5)[H]

-20°C

Ice Packs

Natural Product