Dicycloplatin - CAS 287402-09-9

Dicycloplatin is an inducer of DNA damage. It activates doubly phosphorylated checkpoint kinase 2 (CHK2), breast cancer 1 (BRCA1), and triply phosphorylated p53 to induce DNA damage. Dicycloplatin can cause cell cycle arrest, inhibit proliferation, and trigger apoptosis in prostate cancer PC3 cells and lung cancer NCI/H446 cells. It is applicable for research in the field of cancer.

DNA/RNA Synthesis, Apoptosis

DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Apoptosis

287402-09-9

C12H20N2O8Pt

515.38

O=C(O)C1(C(=O)O)CCC1.O=C1[O-][Pt+2]([O-]C(=O)C12CCC2)([NH3])[NH3]

-20°C

Ice Packs

Small Compound