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Molfinity

Dim16 - CAS 2743448-32-8

Dim16 - CAS 2743448-32-8

MF-0146983-01

$1,787.45 USD
$1,787.45 USD
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Product Details

  • Bioactivity

    Dim16, a dual inhibitor of PCSK9/HMG-CoAR, demonstrates potent activity with an IC50 of 19 nM against PCSK9 and significantly impedes PCSK9-LDLR interaction with an IC50 of 0.8 nM, leading to an enhanced LDL uptake in HepG2 cells [1].

  • Target

    Serine Protease, Others

  • Related Pathways

    Proteases/Proteasome, Others

  • CAS Number

    2743408

  • Molecular Formula

    C29H38IN5

  • Molecular Weight

    583.55

  • SMILES

    IC1=NC=C(C2=NC=C(C=3C=CC=4C=CC=CC4C3)N2CCCC(C)(C)C)N1CCCCCNC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound