Disorazol A - CAS 158181-47-6

Disorazol A1 is a tubulin inhibitor with antifungal properties. It functions by inhibiting tubulin polymerization and disrupting microtubule formation, thereby blocking mitosis and arresting the cell cycle at the G2/M phase, which induces apoptosis. Disorazol A1 also inhibits L929 mouse fibroblasts with an IC50 value of 3 pm and causes accumulation of p53 protein in the nucleus. Disorazol A1 holds potential for cancer research.

Apoptosis, Antifungal, Microtubule Associated

Cytoskeletal Signaling, Apoptosis, Microbiology/Virology

158181-47-6

C43H54N2O10

758.896

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-20°C

Ice Packs

Natural Product