DIZ-3 - CAS 2675490-72-7

DIZ-3, a selective multimeric G-quadruplex (G4) ligand, employs a G4-ligand-dimerizing approach to intercalate into the G4-G4 interface, thereby stabilizing its higher-order structure. This compound effectively induces cell cycle arrest and apoptosis, inhibiting cell proliferation in cancer cells characterized by alternative lengthening of telomeres (ALT) [1].

Others, DNA/RNA Synthesis

Others, DNA Damage/DNA Repair, Cell Cycle/Checkpoint

2675411

C46H44F2N8

746.89

CN1CCN(CC1)c1ccc(cc1)-c1[nH]c(nc1-c1ccc(F)cc1)-c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(cc1)N1CCN(C)CC1)-c1ccc(F)cc1

-20°C

Ice Packs

Small Compound