Dizocilpine - CAS 77086-21-6

Dizocilpine (MK-801) is a selective non-competitive NMDA receptor antagonist with a Kd of 37.2 nM that exhibits anticonvulsant effects. It acts by binding to a site within the NMDA-associated ion channel, blocking the flow of Ca2+, and is commonly used to establish schizophrenia models.

NMDAR, iGluR

Membrane transporter/Ion channel, Neuroscience

77086-21-6

0.9997

C16H15N

221.3

C[C@]12C=3C([C@](N1)(CC=4C2=CC=CC4)[H])=CC=CC3

-20°C

Ice Packs

Small Compound