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Molfinity

DK419 - CAS 2102672-22-8

DK419 - CAS 2102672-22-8

MF-0032741-01

$89.19 USD
$89.19 USD
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Product Details

  • Bioactivity

    DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM. DK419 decreases protein lelvels of Axin2, β-catenin, c-Myc, Cyclin D1 and Survivin.It also induces production of pAMPK.

  • Target

    Survivin, AMPK, c-Myc, Wnt/beta-catenin, CDK

  • Related Pathways

    Apoptosis, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint, Stem Cells, Cytoskeletal Signaling, Chromatin/Epigenetic

  • CAS Number

    2102642

  • Purity

    0.9963

  • Molecular Formula

    C16H8ClF6N3O

  • Molecular Weight

    407.7

  • SMILES

    FC(F)(F)c1nc2cc(Cl)cc(C(=O)Nc3ccc(cc3)C(F)(F)F)c2[nH]1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound