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Molfinity
DL 175 - CAS 2487253-25-6
DL 175 - CAS 2487253-25-6
SKU:MF-0000457-01
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$1,181.10 USD
Regular price
$837.85 USD
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$1,181.10 USD
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Product Details
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Bioactivity
Potent and selective GPR84 biased agonist (EC50 = 33 nM) . Exhibits no significant activity in a panel of 168 other GPCRs. Exhibits bias for G protein signaling pathways. Induces morphological changes in primary murine bone marrow-derived macrophages (BMDMs) in a cellular impedance assay, and promotes phagocytosis by M1 polarized U937 cells. Induces migration of primary human monocytes, but has no effect on macrophage chemotaxis.
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Target
Others
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Related Pathways
Others
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CAS Number
2487253-25-6
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Molecular Formula
C17H14ClNO2
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Molecular Weight
299.75
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound