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Molfinity

DL 175 - CAS 2487253-25-6

DL 175 - CAS 2487253-25-6

SKU:MF-0000457-01

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  • Bioactivity

    Potent and selective GPR84 biased agonist (EC50 = 33 nM) . Exhibits no significant activity in a panel of 168 other GPCRs. Exhibits bias for G protein signaling pathways. Induces morphological changes in primary murine bone marrow-derived macrophages (BMDMs) in a cellular impedance assay, and promotes phagocytosis by M1 polarized U937 cells. Induces migration of primary human monocytes, but has no effect on macrophage chemotaxis.

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    2487253-25-6

  • Molecular Formula

    C17H14ClNO2

  • Molecular Weight

    299.75

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound