DM4-SMe - CAS 796073-68-2

DM4-SMe is a cytotoxic part of antibody-drug conjugates (ADCs) and a metabolite of antibody-maytansin conjugates (AMCs) and tubulin inhibitors, which can also be stabilized by disulfide bonds or thioether The bond binds to the antibody. The IC50 of DM4-SMe on KB cells was 0.026 nM.

Microtubule Associated, ADC Cytotoxin

Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related

796003

C39H56ClN3O10S2

826.46

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-20°C

Ice Packs

Small Compound