DN59 - CAS 869011-94-9

DN59 is a peptide composed of 33 amino acids that mimics the stem region of the dengue virus type 2 E protein. It is capable of inhibiting all four serotypes of the dengue virus (IC50: 2-5 μM) as well as other flaviviruses. DN59 exerts its antiviral activity by interacting directly with viral particles, leading to the release of genomic RNA.

Anti-infection, Others

Microbiology/Virology, Others

869011-94-9

C161H240N38O44S

3443.92

C([C@@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(NCC(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=C(O)C=C5)C(O)=O)=O)[C@H](CC)C)=O)C)=O)=O)=O)[C@H](C)C)=O)CCC(N)=O)=O)=O)CC(C)C)=O)C)=O)CCCCN)=O)=O)[C@H](CC)C)=O)CO)=O)[C@@H](C)O)=O)=O)[C@H](C)C)=O)=O)=O)CC(C)C)=O)CO)=O)=O)=O)CC(O)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCSC)N)=O)C)=O)[C@H](CC)C)=O)CC(C)C)=O)=O)CC(O)=O)=O)[C@@H](C)O)=O)C)=O)C=6C=7C(NC6)=CC=CC7

-20°C

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Peptide