DNA-PK-IN-6 - CAS 2711810-41-0

DNA-PK-IN-6, a robust DNA-PK inhibitor, effectively hampers the activity of DNA-PKcs, thereby significantly impairing the DNA repair mechanism in tumors and instigating apoptosis in cells. Additionally, DNA-PK-IN-6 amplifies the responsiveness of tumor tissues to radiotherapy, overcomes the challenge of drug resistance, and augments its inhibitory impact on a diverse range of solid and hematological tumors[1].

Others, DNA-PK

Others, PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair

2711769

C19H21N7O

363.42

CN1C2=C3N(C1=O)CCCCCC=4N5C=C(N=C(N3)N=C2)C(C)=CC5=NC4

-20°C

Ice Packs

Small Compound