DNA2 inhibitor C5 - CAS 35973-25-2

DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM) . DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2.

Others, DNA/RNA Synthesis

Others, DNA Damage/DNA Repair, Cell Cycle/Checkpoint

35946

0.9905

C10H6N2O5

234.16

OC(=O)c1cnc2c(cccc2c1O)[N+]([O-])=O

-20°C

Ice Packs

Small Compound