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Docetaxel trihydrate - CAS 148408-66-6

Docetaxel trihydrate - CAS 148408-66-6

SKU:MF-0003231-01

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  • Bioactivity

    Docetaxel trihydrate (RP-56976 Trihydrate) is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis and that currently plays a central role in the therapy of many solid tumor including breast and lung cancer. Therapy with docetaxel has been associated with a low rate of serum enzyme elevations and rarely to instances of acute hepatic necrosis generally due to severe hypersensitivity reactions or sepsis.

  • Target

    Microtubule Associated, Bcl-2 Family, Apoptosis

  • Related Pathways

    Cytoskeletal Signaling, Apoptosis

  • CAS Number

    148336

  • Purity

    >99.99%

  • Molecular Formula

    C43H59NO17

  • Molecular Weight

    861.95

  • SMILES

    O.O.O.CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)c2ccccc2)[C@]2(O)C[C@H](OC(=O)C(O)C(NC(=O)OC(C)(C)C)c3ccccc3)C(C)=C([C@@H](O)C1=O)C2(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound