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Docetaxel trihydrate - CAS 148408-66-6
Docetaxel trihydrate - CAS 148408-66-6
SKU:MF-0003231-01
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Product Details
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Bioactivity
Docetaxel trihydrate (RP-56976 Trihydrate) is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis and that currently plays a central role in the therapy of many solid tumor including breast and lung cancer. Therapy with docetaxel has been associated with a low rate of serum enzyme elevations and rarely to instances of acute hepatic necrosis generally due to severe hypersensitivity reactions or sepsis.
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Target
Microtubule Associated, Bcl-2 Family, Apoptosis
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Related Pathways
Cytoskeletal Signaling, Apoptosis
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CAS Number
148336
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Purity
>99.99%
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Molecular Formula
C43H59NO17
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Molecular Weight
861.95
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SMILES
O.O.O.CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)c2ccccc2)[C@]2(O)C[C@H](OC(=O)C(O)C(NC(=O)OC(C)(C)C)c3ccccc3)C(C)=C([C@@H](O)C1=O)C2(C)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound