Dolastatin 15 - CAS 123884-00-4

Dolastatin 15, a depsipeptide derived from Dolabella auricularia, is a potent antimitotic agent structurally related to the anti-tubulin agent Dolastatin 10. Dolastatin 15 can be used as an ADC cytotoxin and it induces cell cycle arrest and apoptosis in multiple myeloma cells.

Apoptosis, ADC Cytotoxin, Microtubule Associated

Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related, Apoptosis

123884-00-4

C45H68N6O9

837.072

COC1=CC(=O)N([C@H]1Cc1ccccc1)C(=O)[C@@H](OC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C)C(C)C)C(C)C |t:2,@:48,@@:36|

-20°C

Ice Packs

Peptide