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Domatinostat - CAS 910462-43-0

Domatinostat - CAS 910462-43-0

SKU:MF-0016958-01

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  • Bioactivity

    Domatinostat (4SC202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against Lysine specific demethylase 1 (LSD1) . Phase 1.

  • Target

    Apoptosis, HDAC

  • Related Pathways

    Chromatin/Epigenetic, Apoptosis, DNA Damage/DNA Repair

  • CAS Number

    910419

  • Purity

    0.9974

  • Molecular Formula

    C23H21N5O3S

  • Molecular Weight

    447.51

  • SMILES

    Cn1cc(cn1)-c1ccc(cc1)S(=O)(=O)n1ccc(\C=C\C(=O)Nc2ccccc2N)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound