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Molfinity

Donafenib - CAS 1130115-44-4

Donafenib - CAS 1130115-44-4

MF-0016572-01

$93.25 USD
$93.25 USD
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Product Details

  • Bioactivity

    Donafenib (Bay 43-9006 (D3) ) is a deuterium-labeled Sorafenib which is a multikinase inhibitor (IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively) .

  • Target

    FLT, Ferroptosis, VEGFR, Apoptosis, Autophagy, Raf

  • Related Pathways

    MAPK, Angiogenesis, Autophagy, Tyrosine Kinase/Adaptors, Apoptosis

  • CAS Number

    1130067

  • Purity

    0.9988

  • Molecular Formula

    C21H13ClD3F3N4O3

  • Molecular Weight

    467.84

  • SMILES

    [2H]C([2H])([2H])NC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Isotope products