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Molfinity

Dooku1 - CAS 2253744-54-4

Dooku1 - CAS 2253744-54-4

SKU:MF-0014325-01

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  • Bioactivity

    Dooku1 is an analog of Yoda1 and a selective antagonist of endogenous Piezo1 channels. Dooku1 inhibits Ca2+ entry induced by 2μMYoda1 with IC50 values of 1.3μM (in HEK 293 cells) and 1.5μM (in HUVEC) . Dooku1 inhibits Yoda1-induced aortic relaxation.

  • Target

    Piezo Channel

  • Related Pathways

    Membrane transporter/Ion channel

  • CAS Number

    2253686

  • Purity

    0.9974

  • Molecular Formula

    C13H9Cl2N3OS

  • Molecular Weight

    326.2

  • SMILES

    Clc1cccc(Cl)c1CSc1nnc(o1)-c1ccc[nH]1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound