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Dooku1 - CAS 2253744-54-4
Dooku1 - CAS 2253744-54-4
SKU:MF-0014325-01
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$38.41 USD
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Product Details
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Bioactivity
Dooku1 is an analog of Yoda1 and a selective antagonist of endogenous Piezo1 channels. Dooku1 inhibits Ca2+ entry induced by 2μMYoda1 with IC50 values of 1.3μM (in HEK 293 cells) and 1.5μM (in HUVEC) . Dooku1 inhibits Yoda1-induced aortic relaxation.
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Target
Piezo Channel
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Related Pathways
Membrane transporter/Ion channel
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CAS Number
2253686
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Purity
0.9974
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Molecular Formula
C13H9Cl2N3OS
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Molecular Weight
326.2
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SMILES
Clc1cccc(Cl)c1CSc1nnc(o1)-c1ccc[nH]1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound