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Molfinity

Dorsomorphin - CAS 866405-64-3

Dorsomorphin - CAS 866405-64-3

SKU:MF-0110025-01

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  • Bioactivity

    Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin induces autophagy, and possesses antitumor activity.

  • Target

    TGF-beta/Smad, AMPK, Autophagy

  • Related Pathways

    Chromatin/Epigenetic, Stem Cells, Autophagy, PI3K/Akt/mTOR signaling

  • CAS Number

    866338

  • Purity

    0.9948

  • Molecular Formula

    C24H25N5O

  • Molecular Weight

    399.49

  • SMILES

    C(CN1CCCCC1)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccncc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound