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Dot1L-IN-7 - CAS 2580940-76-5
Dot1L-IN-7 - CAS 2580940-76-5
SKU:MF-0141538-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
Dot1L-IN-7 (compound 25) is a selective and potent inhibitor of telomere silencing 1-like protein (DOT1L) with an IC50 of 1.0 μM. It selectively kills MLL-AF9 cells without affecting the growth of E2A-HLF cells.
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Target
Histone Methyltransferase, Others
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Related Pathways
Chromatin/Epigenetic, Others
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CAS Number
2580859
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Molecular Formula
C23H27N9O2
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Molecular Weight
461.52
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SMILES
C(CNC(CN1N=C(C(NC2=CC=C(C(C)(C)C)C=C2)=O)N=C1)=O)N3C=4C(C=C3)=C(N)N=CN4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound