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Molfinity

Dot1L-IN-7 - CAS 2580940-76-5

Dot1L-IN-7 - CAS 2580940-76-5

SKU:MF-0141538-01

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  • Bioactivity

    Dot1L-IN-7 (compound 25) is a selective and potent inhibitor of telomere silencing 1-like protein (DOT1L) with an IC50 of 1.0 μM. It selectively kills MLL-AF9 cells without affecting the growth of E2A-HLF cells.

  • Target

    Histone Methyltransferase, Others

  • Related Pathways

    Chromatin/Epigenetic, Others

  • CAS Number

    2580859

  • Molecular Formula

    C23H27N9O2

  • Molecular Weight

    461.52

  • SMILES

    C(CNC(CN1N=C(C(NC2=CC=C(C(C)(C)C)C=C2)=O)N=C1)=O)N3C=4C(C=C3)=C(N)N=CN4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound