Dothiepin - CAS 113-53-1

Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancing noradrenergic neurotransmission by blocking neuronal reuptake. Additionally, it acts as a histamine H1-receptor antagonist and lacks cardiotoxicity. Its analgesic efficacy is noted in conditions such as psychogenic facial pain, idiopathic fibromyalgia syndrome, and rheumatoid arthritis [1].

5-HT Receptor, Histamine Receptor

Neuroscience, Immunology/Inflammation, GPCR/G Protein

59

C19H21NS

295.44

S1C=2C=CC=CC2C(=CCCN(C)C)C=3C=CC=CC3C1

-20°C

Ice Packs

Small Compound