Dovitinib lactate hydrate - CAS 915769-50-5

Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.

VEGFR, FGFR, FLT, c-Kit, PDGFR

Tyrosine Kinase/Adaptors, Angiogenesis

915714

0.9982

C24H27FN6O4

482.51

O.CC(O)C(O)=O.CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1c(N)c2c(F)cccc2[nH]c1=O

-20°C

Ice Packs

Small Compound