Doxorubicin - CAS 23214-92-8

Doxorubicin (Adriamycin) is a fluorescent anthracycline antitumor antibiotic that inhibits Topoisomerase I/II, induces apoptosis and autophagy, downregulates the AMPK signaling pathway, and is commonly used in cancer chemotherapy as well as in models of nephritis and heart failure.

AMPK, ADC Cytotoxin, Topoisomerase

Antibody-drug Conjugate/ADC Related, Chromatin/Epigenetic, PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair

23114

0.9931

C27H29NO11

543.52

COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO

-20°C

Ice Packs

Natural Product