DPP-1-IN-1 - CAS 2781135-27-9

DPP-1-IN-1 (Compound 14) is an orally active inhibitor of cathepsin C (also known as dipeptidyl peptidase I), with an IC50 of 5.31 nM. It effectively suppresses downstream neutrophil elastase activity in neutrophils mediated by cathepsin C. DPP-1-IN-1 is applicable for studying inflammatory diseases.

Serine Protease, Proteasome

Ubiquitination, Proteases/Proteasome

2781099

C23H21FN4O3

420.44

FC=1C=C2C=3C(COC2=CC1C[C@H](NC(=O)[C@@H]4CNCCCO4)C#N)=CC(C#N)=CC3

-20°C

Ice Packs

Small Compound