DPP-8/9 probe-1 - CAS 3020859-80-4

DPP-8/9 probe-1 (compound 20) is a fluorescent probe designed to specifically target and label Dipeptidyl Peptidase DPP8/9, allowing for its visualization through fluorescence microscopy in vitro when active. This compound incorporates a nitrobenzoxadiazole (NBD) tag, demonstrating a high affinity and selectivity for DPP8/9, with significant preference over other S9 family enzymes, evidenced by IC 50 values of 210 nM and 15 nM, respectively. [9] [1]

Proteasome, Others

Others, Ubiquitination, Proteases/Proteasome

3020859-80-4

C31H36FN7O7

637.66

N(C(OCCOCCNC=1C=2C(C(N(=O)=O)=CC1)=NON2)=O)C34CC5(NCC(=O)N6CC=7C(C6)=CC(F)=CC7)CC(C3)CC(C4)C5

-20°C

Ice Packs

Dye-Reagents