Dracorhodin perchlorate - CAS 125536-25-6

Dracorhodin perchlorate inhibits cell growth, and induces apoptosis in fibroblasts in a dose-and time-dependent manner, arresting cell cycle at G1 phase, may as a candidate for anti-breast cancer. Dracorhodin perchlorate can inhibit high glucose-induced serum and glucocorticoid induced protein kinase 1 (SGK1) and fibronectin (FN) expression in human mesangial cells, and this may be part of the mechanism of preventing and treating renal fibrosis of DN.

MDM-2/p53, Apoptosis, Caspase, Akt, NF-κB, PARP, PI3K, ROS, TLR

Immunology/Inflammation, Chromatin/Epigenetic, PI3K/Akt/mTOR signaling, Proteases/Proteasome, NF-κB, Cytoskeletal Signaling, DNA Damage/DNA Repair, Apoptosis

125505

0.9899

C17H15ClO7

366.75

[O-][Cl](=O)(=O)=O.COc1c(C)c(O)cc2[o+]c(ccc12)-c1ccccc1

-20°C

Ice Packs

Natural Product