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DRI-C21045 - CAS 2101765-81-3

DRI-C21045 - CAS 2101765-81-3

MF-0022153-01

$42.14 USD
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Product Details

  • Bioactivity

    Dri-c21045 showed concentration-dependent inhibition of NF-kB activation and all CD40L induced by B cell proliferation with IC50 of 17.1 μM and 4.5 μM, respectively. Dri-c21045 is an effective selective inhibitor of CD40-CD40L synergistic stimulator protein-protein interaction (PPI) with IC50 of 0.17 μM.

  • Target

    NF-κB, TNF

  • Related Pathways

    NF-κB, Apoptosis

  • CAS Number

    2101681

  • Purity

    0.981

  • Molecular Formula

    C32H24N2O7S

  • Molecular Weight

    580.61

  • SMILES

    COC(=O)c1ccc(cc1)C(=O)Nc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1cccc2cccc(c12)S(O)(=O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound