Droxinostat - CAS 99873-43-5

Droxinostat (NS 41080) is a selective HDAC inhibitor, primarily targeting HDACs 6 and 8 with IC50 values of 2.47 μM and 1.46 μM, respectively. It is over 8-fold more selective against HDAC3 and shows no inhibition for HDAC1, 2, 4, 5, 7, 9, and 10.

Apoptosis, HDAC

DNA Damage/DNA Repair, Chromatin/Epigenetic, Apoptosis

99825

0.9983

C11H14ClNO3

243.69

Cc1cc(Cl)ccc1OCCCC(=O)NO

-20°C

Ice Packs

Small Compound