1 1

Molfinity

DS-1205 - CAS 1855860-24-0

DS-1205 - CAS 1855860-24-0

MF-0011758-01

$58.59 USD
$42.25 USD $58.59 USD
Sale Sold out
Taxes included.
Size
View full details

Product Details

  • Bioactivity

    DS-1205 is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205 also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205 can inhibit cell migration in vitro and tumor growth in vivo[1].

  • Target

    TAM Receptor, c-Met/HGFR, Trk receptor

  • Related Pathways

    Tyrosine Kinase/Adaptors

  • CAS Number

    1855860-24-0

  • Purity

    0.9975

  • Molecular Formula

    C41H42FN5O7

  • Molecular Weight

    735.8

  • SMILES

    COc1cc(ccc1OC[C@H]1COCCO1)-c1cnc(N)c(c1)-c1ccc(NC(=O)c2cn(CC3CCOCC3)cc(-c3ccc(C)cn3)c2=O)cc1F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound