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Molfinity

DS-437 - CAS 1674364-87-4

DS-437 - CAS 1674364-87-4

SKU:MF-0032768

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  • Bioactivity

    DS-437 is a dual PRMT5/7 inhibitor with IC50 values of 6 μM and also inhibits DNMT3A and DNMT3B with IC50 values of 52 μM and 62 μM, respectively. Additionally, DS-437 inhibits the methylation of FOXP3.

  • Target

    Histone Methyltransferase, Others

  • Related Pathways

    Chromatin/Epigenetic, Others

  • CAS Number

    1674273

  • Molecular Formula

    C15H23N7O4S

  • Molecular Weight

    397.45

  • SMILES

    CCNC(=O)NCCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound