DSM705 - CAS 2653225-38-6

DSM705 is a pyrrole-based inhibitor of Dihydroorotate Dehydrogenase (DHODH) . It demonstrates high potency in the nanomolar range against Plasmodium DHODH and Plasmodium parasites, while not interfering with mammalian DHODHs. DSM705 shows significant efficacy as an antimalarial compound.

Others, Parasite, Dehydrogenase

Others, Metabolism, Microbiology/Virology

2653181

C19H19F3N6O

404.397

C[C@@H](NC(=O)c1[nH]cc(c1C)C1(CC1)c1ccc(nc1)C(F)(F)F)c1nnc[nH]1

-20°C

Ice Packs

Small Compound