DSP-0390 - CAS 2376765-57-8

DSP-0390 is an oral inhibitor of emopamil binding protein (EBP) . It effectively suppresses the EBP enzyme, which is involved in a critical late-stage step of cholesterol biosynthesis. By inhibiting the synthesis of new cholesterol, DSP-0390 selectively induces cytotoxicity in rapidly proliferating GBM cells. In human GBM xenograft models, DSP-0390 has demonstrated significant antitumor activity.

2376700

C23H30ClN3O2

415.96

CC1(C)[C@@]2(CC3(CO[C@]2(C=4C(O1)=CC(Cl)=CC4)[H])CCN(CCN5C=CN=C5)CC3)[H]

-20°C

Ice Packs

Small Compound