DSP-1053 benzenesulfonate - CAS 1176326-78-5

DSP-1053, a benzylpiperidine derivative, is a potent serotonin transporter (SERT) inhibitor with a dissociation constant (K_i) of 1.02 nM and exhibits partial agonistic activity at the 5-HT_1A receptor with a K_i of 5.05 nM, indicating its potential as an antidepressant.

5-HT Receptor, Serotonin Transporter, Others

GPCR/G Protein, Neuroscience, Others

1176243

C32H38BrNO7S

660.62

O=C1C2=CC(=CC=C2OCC1)CCN3CCC(CC4=CC=C(Br)C(OCCOC)=C4)CC3.O=S(=O)(O)C=1C=CC=CC1

-20°C

Ice Packs

Small Compound